Bebidas endulzadas en adultos jóvenes y su asociación con adiposidad y riesgo metabólico / Sweetened beverages in young adults and its association to adiposity and metabolic risk

Resumen: Objetivo: Estimar la asociación entre consumo de bebidas endulzadas (BE) con indicadores de adiposidad y riesgo metabólico en adultos jóvenes. Material y métodos: Se analizó la frecuencia de consumo de alimentos, índice de masa corporal (IMC), circunferencia de cintura (CC), grasa corporal (PGC), glicemia y triglicéridos de 931 participantes seleccionados aleatoriamente (Región de Valparaíso, Chile), mediante modelos de regresión múltiple, controlando factores de confusión. Resultados: La mediana de edad fue 24.9 años; 94% (IC95% :92.3-95.3) de los participantes consumía BE, 33.1% de ellos consumía más de dos porciones (≥500 ml) diarias, que se asoció con incremento en glicemia (ambos sexos) (β=2.17; p=0.007) y con IMC (β=1.48, p=0.04), CC (β=4.50; p=0.009) y PGC (β=3.02; p<0.001) sólo en mujeres. Conclusión: La alta ingesta de BE incrementa la glicemia en adultos jóvenes y los indicadores de adiposidad en mujeres, antecedentes relevantes para formular políticas que disminuyan el consumo de BE y sus consecuencias.

Abstract: Objective: To estimate the association between sweetened beverages (SB) consumption with adiposity indicators and metabolic status among young Chilean adults. Materials and methods: We analyzed food frequency consumption, body mass index (BMC), waist circumference (WC), body fat percentage (BFP), glucose and triglycerides in 931 young adults randomly selected from Valparaiso Region using multivariate regression models controlling confusion and interactions factors. Results: The median age was 24.9 years; (95%CI: 92.3-95.3) reported SB consumption, 33.1% received more than two portions (≥500 ml) daily what was associated with an increase in glycemia (β=2.40; p=0.024) (both sexes), with BMI (β=1.48, p=0.04), WC (β= 4.50; p=0.009) and BFP (β=3.02, p< 0.001) only in women. Conclusion: High consumption of SB increases glycemia in young adults and only in women, indicators of adiposity, relevant antecedents to formulate policies that decrease SB consumption and its consequences.

Salud y nutrición del niño indígena chileno (Mapuche) / The health and nutrition of indigenous children in Chile (Mapuche) / Saúde e nutrição da criança indígena chilena (Mapuche)

El objetivo de este trabajo fue realizar una revisión de la situación de salud y nutrición del niño indígena chileno, específicamente del Mapuche, en lo publicado en las bases de datos de referencias bibliográficas y en investigaciones específicas que tienen base poblacional. Para este trabajo se buscó lo publicado en PubMed, LILACS, organismos nacionales e internacionales, durante los últimos 15 años. Desde el 2006 hasta el 2015 la proporción de pobres era mayor en los indígenas, con disminución de la brecha de 16% el 2006 a 7,7% el 2015 (p < 0,001). En la primera década de este siglo la mortalidad infantil en los niños indígenas tenía una tasa de 17,1/1.000 nacidos vivos, mientras en los no indígenas era de de 8,8/1.000 y, en el seguimiento de cinco años, la brecha se mantuvo (p < 0,001). Los recién nacidos con peso < 2,500g el año 2000 no superaban el 6% (5,6% en no indígenas y 5,2% en los indígenas). La talla baja al ingreso a la escuela era 8,4% en los escolares indígenas y 3,1% en los no indígenas, disminuyendo a 3,7 en los indígenas y 2,6% en los no indígenas el 2004, la obesidad en cambio aumentó más en los indígenas, llegando a 24,2 y 25,3% en los no indígenas (p < 0,001). La menarquia se presentó cuatro meses más tarde en las indígenas (12,7 años) y el índice de masa corporal, circunferencia de cintura y el porcentaje de grasa, fueron significativamente mayores en las indígenas en el momento de la telarquia, así como la frecuencia de exceso de peso (55% vs. 42% en las no indígenas). Los niños Mapuche presentan una condición de salud y nutrición favorable, comparada con los indígenas de otros países del continente, sin embargo, aun existe una brecha adversa -comparada con los no indígenas-, en que la desigualdad desfavorece al niño indígena y esta debe ser reconocida y corregida.

The aim of this study was to conduct a review of the health and nutritional status of Chilean indigenous children, specifically Mapuche children, as published in the literature and specific population-based studies. The searches were conducted in PubMed and LILACS in the last 15 years. From 2006 to 2015, the poverty rate was higher in the indigenous population, with a decrease in the gap from 16% in 2006 to 7.7% in 2015 (p < 0.001). In the first decade of this century, infant mortality in indigenous children was 17.1/1,000 live births, while in non-indigenous children it was 8.8/1,000, and the gap was maintained in the five-year follow-up (p < 0.001). Newborns with birthweight < 2,500g in the year 2000 did not reach 6% (5.6% in non-indigenous and 5.2% in indigenous children). Low height at first school enrollment was 8.4% in indigenous schoolchildren and 3.1% in non-indigenous children, decreasing to 3.7% in indigenous children and 2.6% in non-indigenous children in 2004, while obesity increased more in indigenous children, reaching 24.2% in indigenous and 25.3% in non-indigenous children (p < 0.001). Menarche appeared four months later on average in indigenous girls (12.7 years), and body mass index, waist circumference, and fat mass were significantly greater in indigenous girls at the time of thelarche, as was the overweight rate (55%, vs. 42% in non-indigenous). Mapuche children show favorable health and nutritional status compared to indigenous children elsewhere in Latin America, but there is still an adverse gap compared to non-indigenous Chilean children. This inequality affecting indigenous Chilean children should be acknowledged and corrected.

O objetivo deste trabalho foi realizar una revisão da situação da saúde e nutrição da criança indígena chilena, especificamente da Mapuche, nas publicações relacionadas em bases de dados de referências bibliográficas e em pesquisas específicas que têm base populacional. A pesquisa foi realizada em publicações relacionadas: PubMed, LILACS, organismos nacionais e internacionais, nos últimos 15 anos. Desde 2006 até 2015 a proporção de pobres era maior nos indígenas, com diminuição de uma diferença de 16% em 2006 a 7,7% em 2015 (p < 0.001). Na primeira década de este século a mortalidade infantil nas crianças indígenas teve una taxa de 17,1/1.000 nascidas vivas, enquanto nos não indígenas era de 8,8/1.000 e, em um acompanhamento de cinco anos, a diferença se manteve (p < 0,001). Os recém-nascidos com peso < 2.500g no ano de 2000 não superavam 6% (5,6% em não indígenas e 5,2% nos indígenas). A baixa estatura ao momento do ingresso na escola era 8,4% nos escolares indígenas e 3,1% nos não indígenas, diminuindo a 3,7 nos indígenas e 2,6% nos não indígenas em 2004, a obesidade pelo contrário teve um aumento maior nos indígenas, chegando a 24,2 e 25,3% nos não indígenas (p < 0,001). A menarca ocorreu quatro meses mais tarde nas indígenas (12,7 anos) e o índice de massa corporal, circunferência da cintura e a porcentagem da gordura, foram significativamente maiores nas indígenas no período da telarca, à semelhança da frequência do sobrepeso (55% vs. 42% nas não indígenas). As crianças Mapuche apresentam uma condição de saúde e nutrição favorável, comparada com os indígenas de outros países do continente, no entanto, ainda existe uma brecha adversa - comparada com os não indígenas - , onde a desigualdade desfavorece a criança indígena e por isso deve ser reconhecida e corrigida.

Patrón de tabaquismo y nivel socioeconómico en dos cohortes de adultos jóvenes / Pattern of smoking and socioeconomic status in two cohorts of young adults

Background: One in five deaths that occur in Chile can be attributed to smoking whose prevalence remains high, despite interventions aimed at reducing it. Aim: To compare the prevalence of smoking and its intensity among young adults born 15 years apart and determine their association with socioeconomic status (SES). Material and Methods: Two cohorts of young adults living in the Valparaiso Region of Chile were evaluated in the third decade of life. Cohort 1 was evaluated between 2000 and 2002 (n = 1232) and cohort 2 between 2014 and 2017 (n = 1078). Results: In cohort 1, 57.5% (95% Confidence Interval (CI) 54.6-58.7) of the subjects reported smoking, with a median of 3 (Interquartile range (ICR:1-6) cigarettes/day. This percentage fell to 40.2% (CI: 37.5-43.1) with a similar median in cohort 2. Analyzing cohort 2, the odds ratio (OR) for smoking was 2.24 (CI 1.48-3.38) in the medium SES, compared with the medium high SES. The figures for low medium and low SES were 2.72 (CI: 1.85-3.99) and 3.01 (1.85-4.88). Similarly, in this cohort there was a significantly higher risk of being a heavy smoker in lower SES. No associations between smoking or its intensity and SES were observed in cohort 1. Conclusions: Smoking behavior has decreased among young adults evaluated at the same age in two generational cohorts in the third decade of life. In the most recent cohort analyzed, smoking and its intensity increase along with a decrease in SES.

Índice, carga glicémica y fibra dietética de los alimentos y su asociación con resistencia a la insulina en adultos chilenos / Glycemic index, glycemic load and dietary fiber of foods and its association with insulin resistance in Chilean adults

El Índice y Carga Glicémica (IG y CG) categorizan los alimentos según su capacidad de incrementar la glicemia, considerando cantidad y calidad de hidratos de carbono consumidos. Diferentes estudios han postulado que una dieta con IG y CG altos y bajo consumo de fibra incrementan la glicemia e insulinemia, aunque con resultados heterogéneos.El objetivo de este estudio fue analizar la asociación entre IG, CG e ingesta de fibra y valores HOMA-IR en adultos jóvenes. En una muestra representativa de 738 personas que tenían entre 32 y 38 años, nacidos en el Hospital de Limache, Región de Valparaíso, Chile, se recogió información socioeconómica, de salud, se determinó estado nutricional, glicemia, insulina basal y HOMA, y con la encuesta de frecuencia de consumo se estimó IG, CG e ingesta de fibra. Se construyeron modelos de regresión múltiple, controlando efectos de confusión e interacción. En modelos ajustados, se observó que por cada 10 unidades que aumenta el IG y CG de la dieta en individuos con exceso de peso, aumenta el HOMA-IR en 0,31 (p=0,042) y 0,03 (p=0,012), respectivamente y por cada 10 gramos que aumenta la fibra total y soluble, disminuye el HOMA-IR en 0,10 (p=0,04) y 0,62 (p=0,034) respectivamente. En personas sin exceso de peso no hubo estos efectos. Existe una asociación directa entre el aumento de IG y CG de los alimentos y el incremento de HOMA-IR sólo en individuos con exceso de peso y una asociación inversa entre ingesta de fibra dietética total y soluble y HOMA-IR(AU)

Glycemic index, glycemic load and dietary fiber of foods and its association with insulin resistance in Chilean adults. Glycemic index and glycemic load (GI and GL) categorize foods according to their ability to increase blood sugar levels, considering quantity and quality of carbohydrates consumed. Different studies have postulated that a high GI and GL diet and low fiber intake increased glycemia and insulinemia, although with heterogeneous results. The aim of this study was to analyze the association between GI, GL and fiber intake and HOMA-IR values in young adults. In a representative sample of 738 people aged between 32 and 38 years old, born in the Limache’s Hospital, Valparaiso, Chile, socioeconomic and health information, nutritional status, basal glycemia, insulin and HOMA were collected. With a food frequency questionnaire, GI, GL and fiber intake were estimated. Multiple regression models were constructed, controlling confounding and interaction effects. In adjusted models, it was found that for every 10 units that increases diet GI and GL in overweight individuals, HOMA- IR increases in 0.31 (p = 0.042) and 0.03 (p = 0.012) respectively, and for every 10 grams that increases total and soluble fiber intake, HOMA-IR reduces in 0.10 (p = 0.04) and 0.62 (p = 0.034) respectively. In people without overweight such effects were not observed. There was a direct association bet- ween increased GI and GL foods and increased HOMA-IR only in individuals with overweight and an inverse association between total and soluble fiber intake and HOMA-IR(AU)

Síndrome metabólico e inflamación en adultos: un estudio poblacional / Association of C reactive protein levels with metabolic syndrome in adults: a population-based study

Background: Metabolic syndrome is highly prevalent among adults in Chile and represents a health risk. Aim: To determine the relationship between metabolic syndrome (MetS) and its components, with C reactive protein levels (CRP) as an inflammation marker. Material and Methods: The population studied consisted of 736 individuals born in a hospital from Valparaíso Region, aged between 32-38 years at the time of the study. MetS was identified according to the Adult Treatment Panel (ATP) III guidelines and inflammation was measured using ultra-sensitive CRP. This parameter was classified as normal for values from 0 to 3 mg/L, high for values from 3.01 to 10 mg/L and very high for values > 10 mg/L. Results: Median CRP was in the normal range (1.9 mg/L, interquartile range 0.7-5.2) and was higher among women than men (2.2 and 1.4 mg/L respectively, p < 0.01). Twenty seven percent of participants had MetS. One-fourth had high blood glucose values, one-third had high triglyceride levels and 28% had blood pressure values over those established as normal in MetS. Elevated waist circumference (WC) and low HDL cholesterol were found among almost 50% of participants. A relationship between MetS and high CRP was only found among men with an Odds ratio (OR) of 2.04 (95% confidence intervals (CI): 1.11-3.73). The same association was observed for high triglyceride levels with an OR of 2.02 (CI: 1.17-3.49) and high WC with an OR of 3.89 (CI: 2.06-7.36). Among women, the only relationship observed was between abdominal obesity and very high CRP with an OR of 2. 65 (CI: 1.20-5.84). Conclusions: Metabolic syndrome, high triglyceride levels, and abdominal obesity were associated with inflammation only in men.

Variación secular de los nacimientos, peso y longitud al nacer: perspectiva local / Secular variation of births, weight and length at birth: Local perspective

Objetivo: Analizar la evolución de los nacimientos y medidas antropométricas al nacer entre 1974-2011 en el Hospital de Limache, Región de Valparaíso, Chile. Pacientes y métodos: Se construyeron series de tiempo de nacimientos, peso y longitud al nacer, peso y talla baja al nacer. Se modelaron las tendencias con regresiones multivariadas usándose splines para representar los cambios de tendencia por década. Resultados: La serie comprende 17.574 nacimientos. Hubo un aumento de los nacimientos/año en los 70 (30/año) y disminución de 17 y 22 nacimientos/año en los 80 y 90 (p < 0,001); después, sin tendencia significativa. Los recién nacidos entre 2000-2011 registran 266 g más que los de la década de los 70 (p < 0,001), alcanzando actualmente en promedio 3.530 g. El bajo peso al nacer disminuyó de 8% en los 70 a 1,1% después de 2000. La longitud al nacer incrementó 1 cm en 37 años, con disminución de la talla baja de 7,6% a 2,1% en el periodo estudiado. Conclusión: Los nacimientos en el Hospital de Limache disminuyeron y las medidas antropométricas al nacer mejoraron; sin embargo, hay que considerar los posibles sesgos que distorsionan estas estimaciones.

Objective: To analyse the outcomes of births and anthropometric measurements at birth of children born between 1974 and 2011 at Limache Hospital (Valparaíso, Chile). Patients and method: Times series were constructed of births, weight and length at birth, and low weight and length at birth. The trend was modelled with linear and logistical regressions using splines to represent breaks in the trend by decade. Results: The series includes 17,574 births. There was an increase in births per year in the 1970s (30/year) and declines in them to 17 and 22 births/year in the 1980s and 1990s, respectively (P < .001), with no significant trend thereafter. Newborns from 2000 to 2011 weighed 266 grams more than those in the 1970s (P < .001), and have now reached a mean weight of 3,530 g. Low birthweight fell from 8% in the 1970s to 1.1% after 2000. Birth length increased by 1 cm in the 37 years studied, with a reduction of low birth length from 7.6% to 2.1% during the period. Conclusion: Live births in the Limache Hospital declined, and anthropometric measurements at birth improved in the years analysed. This information is useful in developing interventions, taking into account the possible selection biases that could distort these estimates and their interpretation.

Ingesta de bebidas azucaradas analcohólicas e índice de masa corporal en escolares chilenos / Intake of sugar-sweetened non-alcoholic beverages and body mass index: A national sample of Chilean school children

Objetivo. Estimar la asociación entre la ingesta de bebidas azucaradas analcohólicas y el índice de masa corporal (IMC) en escolares chilenos. Material y métodos. Se analizaron datos de frecuencia de consumo de alimentos en escolares de entre 6 y 18 años de edad. Se estimó la asociación entre el consumo de bebidas azucaradas y el IMC a través de modelos de regresión lineal multivariada. Resultados. El 92% (IC95%:90-94) consume bebidas azucaradas diariamente, con medianas de ingesta de 424 ml (p25-p75:212-707). En los escolares de 6 a 13 años, cada incremento de una porción diaria de gaseosas y refrescos con azúcar se asocia con 0.13 puntajes z más de IMC (IC95%:0.04-0.2;p=0.01). Conclusiones. El consumo de bebidas azucaradas en escolares chilenos es diario y alcanza medianas de ingesta cercanas a medio litro. Existe asociación entre el consumo de bebidas azucaradas y mayor IMC.

Objective. To estimate the association between the intake of sugar-sweetened non-alcoholic beverages and body mass index (BMI) in Chilean school children. Materials and methods. Food consumption frequency data were analyzed for school children aged 6 to 18. The association between consumption of sugar-sweetened beverages and BMI was estimated by multivariate lineal regression models. Results. Sugar-sweetened beverages are consumed on a daily basis by 92% (95%CI:90-94) of subjects with daily intake medians of 424 mL (p25-p75:212-707). Every extra daily portion of sugar-sweetened beverages consumed by school children aged 6 to 13 is associated with 0.13 BMI z-scores (95%CI:0.04-0.2;p=0.01). Conclusions. School children consume sugar-sweetened beverages daily with intake medians close to 0.5L. There is an association between sugar-sweetened beverage consumption and higher BMI in Chilean school children.

Consumo de frutas, verduras y presión arterial: Un estudio poblacional / Fruit and vegetable intake, and blood pressure: A population research

Se ha descrito que consumir frutas y verduras disminuye la presión arterial. Sin embargo, no está clara la magnitud del efecto según la cantidad consumida. El objetivo de este estudio fue analizar la asociación entre consumo de frutas y verduras, y presión arterial. Se realizó un estudio transversal en una muestra aleatoria de 777 adultos entre 32 y 38 años de la Región de Valparaíso, Chile. Se midió presión arterial sistólica (PAS) y diastólica (PAD), y se aplicó una encuesta de tendencia de consumo cuantificada del último mes. La ingesta de frutas y verduras se dividió en tres grupos: menor a 200 g, 200 a 400 g, mayor a 400 g. Para el análisis se utilizaron modelos de regresión lineal múltiple ajustados por sexo, IMC, actividad física, nivel socioeconómico, tabaquismo e ingesta de sodio. Se observó que a medida que aumenta la ingesta de frutas y verduras disminuye la presión arterial sistólica(β=-3,37; IC 95%: -6,45 a -0,29; en consumo entre 200 y 400 g) (β=- 4,02; IC 95%: -7,06 a -0,98; en consumo mayor a 400 g), mientras que en la presión diastólica solamente se ve el efecto en los que cumplen la recomendación de la OMS de consumir más de 400 g al día (β-2,87; IC=-5,17 a -0,57). Se concluye que consumir frutas y verduras en cantidades mayores a 400 g, tiene un efecto protector en el aumento de la presión arterial tanto sistólica como diastólica.

Consuming fruits and vegetables is known to lower blood pressure. However, it is unclear how much should be consumed in order to achieve this effect. The aim of this study was to analyze the association between fruit and vegetable consumption and blood pressure. A cross-sectional study was conducted among a random sample of 777 adults between the ages of 32 and 38 from the Region of Valparaiso, Chile. Systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured, and a survey was carried out to quantify consumption trends over the past month. The fruit and vegetable intake was divided into three groups: less than 200 g, 200-400 g, and more than 400 g. In the analysis, multiple linear regression models were used and were adjusted for sex, BMI, physical activity, socioeconomic status, smoking, and sodium intake. It was observed that increasing intake of fruits and vegetables lowers the systolic blood pressure (β = -3.37 , 95% CI : -6.45 to -0.29; for consumption between 200 and 400 g ) (β =-4.02 , 95% CI: -7.06 to -0.98; for consumption great than 400 g), while an effect on diastolic pressure is only seen in those who meet the WHO recommendation of consuming more than 400 g per day (β -2,87, CI = -5.17 to -0.57). In conclusion, consuming fruits and vegetables in amounts larger than 400 g per day, provides a protective effect against increases in both systolic and diastolic blood pressure.

Evolución del síndrome metabólico y de sus componentes en un seguimiento de 10 años en adultos de la Región de Valparaíso / Evolution of the metabolic syndrome and its components in a follow up of 10 years in adults from Valparaíso region

Background: Metabolic syndrome is a risk factor for cardiovascular diseases and cancer. Its frequency is increasing steadily Aim: To evaluate the prevalence of metabolic syndrome (MS) and its components in a 10-year tracking study of young adults. Material and Methods: Concurrent cohort study of subjects born between 1974 and 1978. They were evaluated between 2000 and 2002 and between 2010 and 2012 to determine the frequency of MS and its components (high blood glucose, waist circumference [WC], triglycerides, blood pressure and low HDL cholesterol), according to ATP III criteria. Attrition was handled using the reciprocal of the probability of remaining in the study. Result: During the first evaluation, the prevalence of metabolic syndrome was 9.3%, confidence interval (CI): 7.5-11.1), with no gender differences. Ten years later, the prevalence of MS increased significantly to 27.6% (CI: 24.7-29.9) and was more common in women than men (30.4 and 23.8% respectively, p < 0.014). The components of MS also increased from one period to another: hyperglycemia, from 5.2% (CI: 4-7) to 24.4% (CI: 22-27); high triglyceride levels from 17.6% (CI: 15-20) to 35.3% (CI: 32-38); high blood pressure from 14.7 (CI: 13-18) to 30.2% (IC: 28-33) and high WC: 16.9% (CI: 15-19) to 41.5% (CI: 39-45). In both evaluations, there was a greater frequency of high triglycerides and high blood pressure among men, and greater frequency of low HDL and high WC among women. Hyperglycemia only showed differences by gender in the second measurement, and was greater among men. Conclusions: There was a marked increase in metabolic syndrome and its components in a 10-year interval, which is a warning sign of future cardiovascular risk.

Edad de menarquia y ascendencia indígena: Un estudio poblacional en Chile / Age at menarche and indigenous ancestry: A population study in Chile

Background: The age at menarche may influence decisively health and disease in women. It also indicates the beginning of the reproductive period and, as a consequence, the possibility of biological continuity for the human species. Genetic and environmental determinants define the age of menarche and can explain differences found among different populations. Aim: To determine the age at menarche among adolescents with different levels of indigenous descent (parental indigenous surnames), considering the effect of socioeconomic and demographic factors. Material and Methods: An observational study of historic cohorts of8.624 girls from the Arauca-nía Region (central-southern Chile) was carried out. Data were collected by health professionals using a previously validated questionnaire. Occurrence of menarche was estimated through survival analysis and compared between groups (according to indigenous parental surnames) adjusted for parents' income and educational level and provenance (rural/urban). Results: Estimated median age of menarche was 151 months (95% Cl: 150-151). In female with four indigenous surnames, menarche occurred two months later than girls without indigenous surnames and with two indigenous surnames (p < 0,001). In girls whose parents had lowest level of schooling, the difference increased to eight months later (p < 0,005). Conclusions: Age at menarche in the group with higher indigenous descent is later even if socio-economic conditions remain stable. Genetic factors might play an important role, however conditions of vulnerability can influence and further delay the onset of reproductive competency.

Socioeconomic status and age at menarche in indigenous and non-indigenous Chilean adolescents / Nivel socioeconómico y edad de la menarquia en adolescentes chilenas indígenas y no indígenas

The objective was to analyze the relationship between socioeconomic status and age at menarche among indigenous and non-indigenous girls in the Araucanía Region of Chile, controlling for nutritional status and mother's age at menarche. A total of 8,624 randomly selected girls from 168 schools were screened, resulting in the selection of 207 indigenous and 200 non-indigenous girls who had recently experienced menarche. Age at menarche was 149.6±10.7 months in the indigenous group and 146.6±10.8 months in the non-indigenous group. Among the non-indigenous, the analysis showed no significant association between age at menarche and socioeconomic status. In the indigenous group, age at menarche among girls with low socioeconomic status was 5.4 months later than among those with higher socioeconomic status. There were no differences in nutritional status according to socioeconomic level. Obesity was associated with earlier menarche. Menarche occurred earlier than in previous generations. An inverse relationship between socioeconomic status and age at menarche was seen in the indigenous group only; low socioeconomic status was associated with delayed menarche, regardless of nutritional status or mother's age at menarche.

El objetivo fue analizar la relación entre nivel socioeconómico y edad de menarquia en adolescentes indígenas y no indígenas de la Región de la Araucanía, Chile, controlando el efecto del estado nutricional, y la edad de menarquia de las madres. Se estudiaron 8.624 niñas de 168 escuelas elegidas aleatoriamente, seleccionando 207 indígenas y 200 no indígenas que habían tenido recientemente la menarquia. La edad de menarquia ocurrió a los 149,6±10,7 meses en indígenas y a los 146,6±10,8 meses en no indígenas. En el grupo no indígena, hubo una relación significativa entre edad de menarquia y nivel socioeconómico. En el grupo indígena, edad de menarquia del nivel socioeconómico bajo fue de 5,4 meses más tarde que el nivel socioeconómico más alto. No se observaron diferencias de estado nutricional por nivel socioeconómico. La obesidad adelantó la menarquia y la edad de menarquia ocurrió antes que la de sus madres. Existe una relación inversa entre nivel socioeconómico y edad de menarquia sólo en el grupo indígena; en los niveles socioeconómicos más bajos la edad de menarquia se retrasa independiente del estado nutricional y de la edad de menarquia de la madre.

¿Qué tipo de intervención tiene mejores resultados en la disminución de peso en adultos con sobrepeso u obesidad? Revisión Sistemática y Metaanálisis

Se ha demostrado que intervenciones basadas en cambios de estilo de vida, tales como dietas y actividad física, provocarían una reducción de peso capaz de disminuir los factores de riesgo cardiovascular. Sin embargo, persiste la interrogante de cuál es el tipo de intervención y duración más efectiva. El objetivo de este trabajo fue evaluar y comparar el efecto en el peso de intervenciones basadas en dieta, ejercicio y una combinación de ambos, en adultos con sobrepeso y obesidad, a los seis y doce meses de ejecución. Se realizó una revisión sistemática y posteriormente un metaanálisis, seleccionándose 12 estudios que cumplieron los criterios de inclusión y nivel de calidad exigido. Las intervenciones con dieta mostraron disminuciones de -6,66 kilos (intervalo de confianza del 95% (IC): -9,04 a -4,28) y -3,80 kilos (IC: -5,50 a -2,10) a los seis y doce meses respectivamente, las intervenciones con ejercicio presentaron reducciones de -2,21 kilos (IC: -4,62 a 0,21) y -2,00 kilos (IC: -5,70 a 1,70) a los seis y doce meses respectivamente y aquellas con dieta más ejercicio reducciones de -10,86 kilos (IC: -13,22 a -8,49) y -6,50 kilos (IC: -8,09 a -4,90) a los seis y doce meses de ejecución. La combinación de dieta y ejercicio fue más efectiva en la disminución de peso en personas con sobrepeso y obesidad, seguida por la dieta, mientras que el ejercicio no tuvo resultados significativos. En los tres tipos de intervenciones el efecto fue mayor durante los primeros seis meses de ejecución.

Evidence has shown that interventions which involve changes in a person’s lifestyle, such as diet and physical activity, lead to weight loss and thus reduce the risk factors of cardiovascular disease. However, the effectiveness and necessary duration of specific interventions are unclear. The purpose of this research was to evaluate and compare the effect on weight of interventions based on diet, exercise and a combination of both. The research subjects were overweight and obese adults, at six and twelve months after the beginning of the intervention. First a systematic review was carried out, followed by a meta-analysis. Initially, 24 studies were selected which met the established criteria for inclusion; twelve of these demonstrated the required level of quality. The diet-based interventions resulted in reductions of -6.66 kilograms (95% confidence interval (CI): -9.04 to -4.28) and -3.80 kilograms (CI: -5.50 to -2.10) at six and twelve months, respectively. Those who engaged in exercise showed a loss of -2.21 kilograms (CI: -4.62 to -0.21) and -2.00 kilograms (CI: -5.70 to -1.70) at six and twelve months, respectively, while those who changed their diets and engaged in exercise showed a loss of -10.86 kilograms (CI: -13.22 to -8.49) and -6.50 kilograms (CI: -8.09 to -4.90) at six and twelve months. The combination of diet and exercise showed the best effect in reducing weight among overweight and obese people, followed by diet alone while exercise alone didn’t reach significant results. The effect of these interventions was greater during the first six months of intervention.

Actividad física y su asociación con factores de riesgo cardiovascular: Un estudio en adultos jóvenes / Physical activity and cardiovascular risk factors among Chilean young men and women

Background: Physical activity (PA) has a protective role in cardiovascular diseases. Aim: To quantify PA in young adults and to correlate it with cardiovascular risk factors. Material and Methods: A cross-sectional study was performed employing the international physical activity questionnaire (IPAQ), to measure the PA of 983 randomly selected young adults from Valparaiso region born between 1974 and 1978. Its results were associated with levels of obesity, insulin resistance and cardiovascular risk factors defined by the National Cholesterol Education Program-Adult Treatment Panel III (NCEP- ATP III) Results: Mean physical activity among men and women was 3731 ± 3923 and 1360 ± 2303 METs-minutes/week, respectively (p < 0.001). Fifty percent of women and 21.5 percent of men had an insuffcient level of physical activity (p < 0.001). Sixty percent of men and 23.4 percent of women had an intense level of physical activity (p < 0.001). There was an inverse association of physical activity and insulin resistance. A high physical activity was protective, specially among men, against a low HDL cholesterol level and high triglyceride levels with Odds Ratios of 0.59 (confdence interval (CI): 0,35-0.98) and 0.49 (CI: 0,27-0,87) respectively, after adjusting for body mass index and age. Conclusions: In this sample, men had higher levels of physical activity, that was protective against insulin resistance and the presence of cardiovascular risk factors.

Telarquia y estado nutricional: Estudio epidemiológico en dos grupos étnicos / Thelarche and nutritional status: An epidemiológical study of two ethnic groups

Background: Improvements in environmental conditions may result in an earlier onset of thelarche. However, its onset is not homogeneous among different population groups. Aim: To assess the relationship between nutritional status, ethnicity and age of thelarche. Material and methods: Cross-sectional study of girls in second through sixth grade, attending 165 schools located in Chile's Araucania region. Of these, 231 girls who presented thelarche (breast button) were selected. The girls' surnames were used to identify their ethncity: indigenous had three or four last names of Mapuche indigenous origin (n =113), while non-indigenous were those who only had Chilean-Spanish last names (n =118). Weight, height, waist circumference and skinfold thicknesses were measured and socio-economic background information was collected through a home interview. Results: The median age of thelarche was 10 years and 4 months, regardless of ethnic group. Multivariant models showed that an increase of one z score unit of body mass index (BMI) decreased the median age of thelarche by 5.6 months (CI: -7.24 to -3.90), controlling for the effect of different covariables. A decrease in one z score of height retards the median age of thelarche by 5.5 months (CI: 4.02 to 6.98). Ethnicity did not influence the age of thelarche. Conclusions: The age of thelarche found by us is similar to that reported in international studies, it comes earlier as weight increases, is delayed as height decreases and is not related to ethnicity.

Estado nutricional en la telarquia y menarquia de adolescentes chilenas indígenas y no indígenas / Nutritional status in telarche and menarche in indigenous and non indigenous chilean adolescents

Se ha señalado que existiría un efecto compensatorio de la desnutrición crónica que induce al exceso de peso y esto seria más evidente en poblaciones indígenas. El objetivo de este trabajo fue establecer la asociación entre etnia indígena (mapuche) y composición corporal en telarquia y menarquia de indígenas y no indígenas. Mediante un diseño transversal, que se inició con un tamizaje de 10.192 niñas de 168 escuelas de la región de la Araucanía en Chile, para identificar 230 adolescentes en telarquia (estadio II de desarrollo de la glandula mamaria): 112 indígenas y 118 no indígenas y 239 en menarquia: 113 indígenas y 126 no indígenas, a quienes se evaluó el índice de masa corporal (IMC), circunferencia de cintura (CC), masa magra (MM) y grasa (MG). El IMC, CC y MM fueron mayores en indígenas en telarquia (p<0,001). En menarquia las diferencias disminuyeron alcanzando valores mayores en indígenas sólo en IMC y MG (p=0,04 y 0,02). Mediante regresión lineal, se observó que pertenecer a la etnia mapuche aumentó el IMC en 0,37 puntajes z, 95 por ciento intervalo de confianza (IC): 0,17-0,58 en telarquia y en 0,44 puntajes z (IC: 0,18-0,70) en menarquia. El ser mapuche se asoció a tener mayor CC, 3,33 cm (IC: 1,67-4,99) en telarquia y 3,17, (IC: 0,73 -5,60) en menarquia, esta procedencia se asocia también a mayor porcentaje de masa magra en telarquia, 1,3 (IC: 0,11-2,43) y mayor masa grasa en menarquia: 2,4 (IC: 1,02- 3,77). Los indicadores de composición corporal en adolescentes indígenas son preocupantes y sugieren que existan programas de fomento de estilos de vida saludable, aprovechando recursos existentes.

A compensatory effect of chronic malnutrition that influences excess of weight has been reported. This effect would be more evident in indigenous populations. The aim of this study was to find out the association between ethnic group (mapuche) and body composition in the telarche and menarche of indigenous and non indigenous adolescents. This was a cross sectional design. At the beginning, a screening of 10,121 girls from 168 schools in the Araucania Region, Chile was done. 230 adolescent in telarche (grade II of the development of the mammary gland) :112 indigenous and 118 non indigenous and 239 in menarche (113 indigenous and 126 non indigenous) were identified. Body mass index (BMI), waist circumference (WC), lean mass (LM) and fat mass (FM) were evaluated. BMI, WC and LM were higher in the indigenous adolescent in telarche. For those with menarche, the differences decreased, reaching with higher values for indigenous girls only in BMI and FM (p=0,04 and 0,02, respectively). Belonging to the indigenous group increased the BMI in 0.37 z scores in telarche (95 percent CI: 0,17-0,58) and 0,44 in menarche (95 percent CI:0,18-0,70). Being mapuche was also associated to higher WC: 3.33 cm (CI 1,67 - 4,99) in telarche and 3,17 cm (CI 0,73-5,60) in menarche and to higher lean mass only for those adolescents with telarche (1,3 CI: 0,11-2,43) and to fat mass only for those with menarche (2,4 CI: 1,02-3,77). The body composition indicators in indigenous adolescents are of concern and underscores the importance of programs to promote healthy lifestyles that take into account resources from the indigenous communities.

Tendência de crescimento de filhos de mães adolescentes / Growth trend of infants of adolescents mothers

OBJETIVO: comparar o crescimento de lactentes filhos de mães adolescentes com o de filhos de mães adultas nos primeiros dois anos de vida. MÉTODOS: estudo de coorte histórica realizado entre 1998 e 2000, comparando o crescimento de dois grupos de crianças do nascimento até completar dois anos de idade. Um dos grupos era constituído por filhos de mães adolescentes (n:127) e o outro por filhos de mães adultas (n:181). Ambos os grupos eram acompanhados regularmente nas duas Unidades Básicas de Saúde da Universidade de São Paulo, integradas ao sistema de público de saúde. Os dados de peso e comprimento, coletados sistematicamente, foram analisados sob a forma de escore Z (NCHS/OMS, 1978). Equações (curvas) de regressão descrevendo o crescimento individual de cada criança foram definidas a partir dos dados coletados. Posteriormente, os valores de escore Z de peso e comprimento em idades exatas (mensais) foram estimados por interpolação, utilizando-se as equações individuais obtidas. RESULTADOS: ao nascimento e aos 24 meses os dois grupos não apresentaram diferença nas médias dos escores Z de peso e comprimento que, contudo, eram inferiores às do referencial (p<0,001). Neste período, apresentaram desempenhos diferentes de crescimento, com uma tendência pior para os filhos de adolescentes, que se afastava da mediana do referencial de maneira significante, (p=0,0008). CONCLUSÃO: Os lactentes de mães adolescentes apresentaram um pior desempenho de crescimento até os dois anos de vida, quando comparados com o dos filhos de mães adultas.

Pobreza y procedencia indígena como factores de riesgo de problemas nutricionales de los niños que ingresan a la escuela / Poverty and indigenous origin as risk factors of nutritional problems among children who enroll in school

OBJETIVO:Determinar el efecto de ser indígena y de la pobreza, en los problemas nutricionales de escolares chilenos. MATERIAL Y MÉTODOS:Se usaron bases de datos de niños que ingresaron a la escuela (1997-2004) que tenían información antropométrica, socioeconómica y origen étnico. Se construyeron modelos de regresión logística para talla baja y obesidad controlando el efecto de la pobreza y la etnia por sexo, edad y año de análisis. RESULTADOS:Se estudió a 1580103 niños: indígenas (7.4%), con talla baja (2.9%) y obesidad (16%). Al estratificar por etnia, los más pobres tuvieron mayor riesgo de talla baja: en indígenas RM: 2.30 (IC95%: 2.27-2.33) y no indígenas RM: 2.29 (IC95%: 2.28-2.30). A la inversa, los escolares más pobres tuvieron menos riesgo de ser obesos (RM: 0.63; IC95%: 0.62-0.64). Ser indígena proporcionó 6% más posibilidad de presentar obesidad, comparado con no ser indígena (RM: 1.06; IC95%: 1.05-1.08). CONCLUSIÓN:. En niños chilenos, la pobreza es factor de riesgo de talla baja pero protector de obesidad independiente de la etnia. El mayor riesgo de obesidad en los escolares indígenas, si bien es pequeño, debe ser una voz de alerta para prevenir en ellos el aumento de las cifras.

OBJECTIVE:To estimate the effect of indigenous ancestry and poverty on nutritional outcomes in Chilean schoolchildren. MATERIAL AND METHODS:We used the national database of children entering to the public educational system in 1997-2004. This includes anthropometric assessment, socioeconomic status and parental surnames, used to derive the ethnic origin. Logistic regression models related poverty and ethnicity on stunting and obesity were done, controlling for sex, age and calendar year. RESULTS:Data convey 1580103 children being 7.4% indigenous; 2.9% had stunting and around 16.0% were obese. Stratifying by poverty, it was shown that the poorest had higher risk of stunting both in indigenous (OR= 2.30; CI95%=2.27-2.33) and non indigenous (OR= 2.29; CI95%= 2.28-2.30). Conversely, poverty was a "protective factor" for obesity (OR= 0.63; CI95%= 0.62-0.64). Indigenous origin showed a significant OR slightly over the null. CONCLUSIONS:In Chilean children, poverty is a risk factor for stunting but still protects from obesity, independent of indigenous origin.

Vigilancia nutricional en escolares chilenos: validez de la información / Nutritional surveillance in Chilean schoolchildren: validity ofthe information

Background: Anthropometry is used to survey health and nutritional situation of the population. Therefore the quality of the information that is being used must be evaluated. Aim: To estímate the agreement in weight, height and nutritional status in schoolchildren, comparing measurements made by teachers in schools and a standardized and supervised team of professionals. Material and methods: Cross sectional study including 927 schoolchildren in 31 schools from 7 counties of Santiago. Schools were randomly chosen and the universe of children attending to first grade was measured. Weight, height and nutritional status collected by teachers and researches, were compared. Results: Total agreement for nutritional status reached 0.67, random-weighted Kappa was 0.40 and weighted Kappa, 0.42. Teachers tended to over diagnose under-nutrition and under diagnose overweight and obesíty measuríng 270 grams less than the qualified team (p <0.001) and 1.7 cm more in height (p <0.001), what is reflected in a difference of less than one point in body mass index (p <0.001). Discrepancies in height and body mass índex were higher in extreme valúes. Conclusions: There is a low agreement between the measurements taken by the research team and teachers. Even though there are discrepancies between measurements, high levéis of overweight and low prevalences of stunting and underweight are kept, reílecting problems with exactitude, but not bias. Corrective actions to improve the quality of information, which should include training programs for teachers, instrument maintenance, supervisión and verification system for data entry, are needed.

Programas destinados a disminuir la desnutrición crónica. una revisón en América Latina / Programs destined to descrease the chronic malnutrition. a review in Latin American

En América Latina la desnutrición crónica afecta al 16 por ciento de los menores de cinco años, y es el resultado de la acumulación de una dieta inadecuada y la recurrencia de enfermedades. El objetivo del trabajo fue analizar el impacto de los programas destinados a mejorar el crecimiento de los menores de 5 años en America Latina, considerando aquellos que han tenido como finalidad aumentar la oferta alimentaria a nivel familiar y entre estos los que han sido evaluados y publicados. Para esto se realizó una revisión bibliográfica en PUBMED, LILACS, SCIELO y de informes de organismos internacionales entre 1995 a 2005. Se identificaron tres tipos de programas: Transferencia Económica Condicionada (PTEC), Alimentación Complementaria (PAC) y Seguridad Alimentaria (PSA). Se reportaron algunas dificultades en su gestión, entre los que destacan que beneficiarios no permanecen el tiempo establecido y los suplementos nutricionales no son aceptados o se diluyen a nivel familiar, Los niños beneficiarios del PTEC alcanzaron ganancias hasta de un centímetro (menores de 36 meses); los del PAC registraron impacto sólo en los más pobres; en tanto los PSA no reportaron efectos demostrables. Este impacto reducido es explicable porque para desarrollar todo el potencial de crecimiento del niño, hay que asegurar intervenciones coordinadas ligados al combate a la pobreza y de esta forma actual sobre sus mecanismos de acción. Por eso no es de extrañar que los programas que presentan mejores resultados sean los que están insertos en una lucha coordinada para disminuir la pobreza, los que presentan una mayor continuidad y cuya acción se ha focalizado prioritariamente en los más vulnerables.